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Antigenic Specificity | CD77 |
Clone | 38.13 |
Host Species | Rat |
Reactive Species | human |
Isotype | IgM |
Format | fluorescein (FITC) conjugate |
Size | 100 tests |
Concentration | n/a |
Applications | FC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD77 (globotriaosylceramide Gb3), also known as the Pk blood group antigen, BLA (Burkitt?s lymphoma associated antigen), or CTH (ceramide trihexoside) is a neutral glycosphingolipid composed of three carbohydrate molecules linked to a lipid moiety in the cell membrane (Gal-alpha1-4Gal-beta1-4Glc-beta1-Cer). It is expressed on germinal center B cells, Burkitt?s lymphoma cells, it can be induced on extrafolicular B cells and it is also found on endothelia and epithelia. CD77 may be involved in elimination of germinal center B cells that fail to produce high affinity antibodies, and serves also as receptor for shiga toxin and verotoxin. |
Immunogen | Daudi cell line (Burkitt?s lymphoma) |
Other Names | globotriaosylceramide Gb3, Gal-alpha1-4Gal-beta1-4Glc-beta1-Cer, P blood group |
Gene, Accession # | n/a |
Catalog # | orb1088486 |
Price | $372 |
Order / More Info | CD77 Antibody from BIORBYT LTD. |
Product Specific References | n/a |
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