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Antigenic Specificity | Ad fiber knob + EPCAM (bispecific) |
Clone | monoclonal |
Host Species | Recombinant Mouse |
Reactive Species | human |
Isotype | n/a |
Format | bispecific |
Size | n/a |
Concentration | n/a |
Applications | FuncS; Promising therapeutic agent; |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recombinant Anti-Ad fiber knob x Anti-EPCAM Bispecific Antibody (Fab-Fv). Recombinant Anti-Ad fiber knob x Anti-EPCAM Bispecific Antibody (Fab-Fv) is designed to be expressed as two polypeptide chains. The heavy chain Fd fragment and light chain of an anti-Ad fiber knob antibody are fused with the VL and VH domains of an anti-EPCAM antibody respectively. It can form natural in vivo heterodimerization. This BsAb can retarget of adenoviral vectors to tumour cells. It can be used in cancer gene therapy to transfer a therapeutic gene into tumour cells aiming at selective and efficient cell killing. |
Immunogen | n/a |
Other Names | Ad fiber knob; Adenovirus fiber knob; adenovirus fiber protein; knob domain of Ad fiber |
Gene, Accession # | n/a |
Catalog # | FABFV-004 |
Price | please inquire |
Order / More Info | Ad fiber knob + EPCAM (bispecific) Antibody from CREATIVE BIOLABS, INC. |
Product Specific References | n/a |