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Antigenic Specificity | B5 Env |
Clone | monoclonal |
Host Species | Recombinant Human |
Reactive Species | n/a |
Isotype | n/a |
Format | unconjugated |
Size | n/a |
Concentration | n/a |
Applications | ELISA; WB; Neut; FuncS; |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Recombinant Anti-B5 Env (aa 20-130) Neutralizing Antibody (V3S-0622-YC38). This product is a human monoclonal antibody that reacts with B5 Env. The antibody displayed high binding affinities to B5 (Kd of 0.2 nM). The mAb inhibited the spread of vaccinia virus as well as variola virus in vitro, protected mice from subsequent intranasal challenge with virulent vaccinia virus, and provided significantly greater protection than that afforded by a previously isolated rat anti-B5 mAb (19C2) or by vaccinia immune globulin. The mAb bound to a conformational epitope between amino acids 20 and 130 of B5. |
Immunogen | n/a |
Other Names | B5 envelope glycoprotein; B5; VACV; Vaccinia virus |
Gene, Accession # | n/a |
Catalog # | V3S-0622-YC38 |
Price | please inquire |
Order / More Info | B5 Env Antibody from CREATIVE BIOLABS, INC. |
Product Specific References | n/a |