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Antigenic Specificity | RELN |
Clone | CBP17816 |
Host Species | Rabbit |
Reactive Species | human; rat; |
Isotype | n/a |
Format | unconjugated |
Size | n/a |
Concentration | n/a |
Applications | WB; |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | NeuroMab™ Anti-Reelin Monoclonal Antibody, Clone NR1001P (CBP17816) |
Immunogen | n/a |
Other Names | Reelin (RELN) [5] is a secreted large extracellular matrix glycoprotein that can help regulate neuronal migration and localization in the developing brain by controlling cell-cell interactions. In addition to playing an important role in early development; Reelin also continues to play a role in the adult brain. [6] It regulates synaptic plasticity by enhancing the induction and maintenance of long-term potentiation. [7] [8] It also stimulates the development of dendrites [9] and dendritic spines [10] and regulates the continued migration of neuroblasts produced in adult neurogenesis sites (such as the subventricular and subgranular regions). It is found not only in the brain; but also in the liver; thyroid; adrenal glands; fallopian tubes; and breasts; and is also low in a range of anatomical regions. [11] |
Gene, Accession # | Gene ID: 5649 |
Catalog # | NRZP-0223-ZP129 |
Price | please inquire |
Order / More Info | RELN Antibody from CREATIVE BIOLABS, INC. |
Product Specific References | n/a |