HHV-2 gD Antibody from CREATIVE BIOLABS, INC.
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| Edit | |
|---|---|
| Antigenic Specificity | HHV-2 gD |
| Clone | monoclonal |
| Host Species | Recombinant Human |
| Reactive Species | HHV |
| Isotype | n/a |
| Format | unconjugated |
| Size | n/a |
| Concentration | n/a |
| Applications | Neut, |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Recombinant Human Anti-HHV-2 gD Antibody (E317). Recombinant Human Antibody (E317) is capable of binding to HHV-2 gD, expressed in HEK 293 cells. Expressed as the combination of a heavy chain (HC) containing VH from anti-HHV-2 gD mAb and CH1-3 region of human IgG and a light chain (LC) encoding VL from anti-HHV-2 gD proteins mAb and CL of human kappa light chain. Exists as a disulfide linked dimer of the HC and LC hetero-dimer under non-reducing condition. The highly inhibitory human monoclonal antibody E317 was previously raised against HSV gD for viral neutralization. E317 directly recognizes the gD-nectin-1 interface and occludes the HVEM contact site of gD to block its binding to either receptor. The binding of E317 to gD also prohibits the formation of the N-terminal hairpin of gD for HVEM recognition. |
| Immunogen | n/a |
| Other Names | gD; US6; type 1 membrane protein; contains a signal peptide; binds cell surface receptors; involved in cell attachment |
| Gene, Accession # | UniProt: Q69467 |
| Catalog # | PABC-161 |
| Price | please inquire |
| Order / More Info | HHV-2 gD Antibody from CREATIVE BIOLABS, INC. |
| Product Specific References | n/a |
CREATIVE BIOLABS, INC.
CREATIVE BIOLABS, INC.
Suite 203
17 Ramsey Road
Shirley NY 11967
P: 1-631-416-1478
F: 1-631-207-8356
info@creative-biolabs.com
http://www.creative-biolabs.com
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