DENV E Antibody from CREATIVE BIOLABS, INC.

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Antigenic SpecificityDENV E
Clonemonoclonal
Host SpeciesRecombinant Mouse
Reactive SpeciesDENV
Isotypen/a
Formatunconjugated
Sizen/a
Concentrationn/a
ApplicationsELISA, Neut, FuncS,
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DescriptionMouse Anti-DENV E Recombinant Antibody (clone 2H12). 2H12 binds to the highly conserved AB loop of domain III of the envelope protein that is poorly accessible in the mature virion. 2H12 neutralization varied between dengue serotypes and strains; in particular, dengue serotype 2 was not neutralized. Because the 2H12-binding epitope was conserved, this variation in neutralization highlights differences between dengue serotypes and suggests that significant conformational changes in the virus must take place for Ab binding. Surprisingly, 2H12 facilitated little or no enhancement of infection.
Immunogenn/a
Other NamesDENV E; Envelope proteins; E proteins
Gene, Accession #n/a
Catalog #HPAB-S0024-YC
Priceplease inquire
Order / More InfoDENV E Antibody from CREATIVE BIOLABS, INC.
Product Specific Referencesn/a
CREATIVE BIOLABS, INC.
CREATIVE BIOLABS, INC.
CREATIVE BIOLABS, INC.
Suite 203
17 Ramsey Road
Shirley NY 11967
P: 1-631-416-1478
F: 1-631-207-8356

info@creative-biolabs.com

http://www.creative-biolabs.com

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