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Antigenic Specificity | Human C4d |
Clone | n/a |
Host Species | n/a |
Reactive Species | human |
Isotype | n/a |
Format | unconjugated |
Size | 1 vial |
Concentration | n/a |
Applications | RUO |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The Eagle Biosciences Anti-Human C4d antibody is described by the majority of publications as an important marker in kidney transplantation but also in heart, liver, and other transplants. Circulating alloantibodies encounter the grafted endothelium as the first target. Living endothelial cells can rapidly eliminate bound antibodies from the cell surface by ``capping'', ``shedding'' or ``internalisation''. C4d is the degradation product of the activated complement factor C4, a component of the classical complement cascade, which is typically initiated by binding of antibodies to specific target molecules. Detection of C4d is regarded as an indirect sign, a ``footprint'' of an antibody response against the allograft. |
Immunogen | n/a |
Other Names | BI-RC4d, C4d |
Gene, Accession # | n/a |
Catalog # | BI-RC4D |
Price | $520 |
Order / More Info | Human C4d Antibody from EAGLE BIOSCIENCES INC. |
Product Specific References | n/a |