MLH1 Antibody from EAGLE BIOSCIENCES INC.
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| Edit | |
|---|---|
| Antigenic Specificity | MLH1 |
| Clone | monoclonal |
| Host Species | Mouse |
| Reactive Species | n/a |
| Isotype | n/a |
| Format | unconjugated |
| Size | 0.1 ml |
| Concentration | n/a |
| Applications | RUO |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | MutL Homolog 1 (MLH1) is a protein involved in the mismatch-repair pathway. This protein is commonly associated with hereditary non-polyposis colorectal cancer, as the MLH1 gene is frequently mutated in patients with this cancer. Studies have shown MLH1 to be deficient in a high percentage of patients with microsatellite instability, as well as endometrial and ovarian cancers. Use of Anti-MLH1 is optimized when paired in an IHC panel with MSH6, MSH2, and PMS2. Anti-MLH1 is useful in the detection of MLH1 in a number of normal and neoplastic tissues, and for identifying a loss of MLH1 in tumours that are microsatellite-unstable. |
| Immunogen | n/a |
| Other Names | IgG2a |
| Gene, Accession # | n/a |
| Catalog # | IHC409-100 |
| Price | $125 |
| Order / More Info | MLH1 Antibody from EAGLE BIOSCIENCES INC. |
| Product Specific References | n/a |
EAGLE BIOSCIENCES INC.
EAGLE BIOSCIENCES INC.
20A NW Blvd., Suite 112
Nashua NH 03063
P: 617-419-2019
P: 866-411-8023
F: 617-419-1110
info@EagleBio.com
http://www.EagleBio.com
Profile of EAGLE BIOSCIENCES INC.