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Antigenic Specificity | RCC2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, (presumed: dog, horse, porcine, panda, orangutan, monkey, chimpanzee, white-tufted-ear marmoset, small-eared galago, little brown bat, northern white-cheeked gibbon, african elephant, cr |
Isotype | n/a |
Format | antigen affinity purified |
Size | 100 µl |
Concentration | 100 µg/ml |
Applications | IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-RCC2 IHC Antibody, Affinity Purified. RCC2 (regulator of chromosome condensation 2) is a member of the RCC1 family of guanine nucleotide exchange factors. RCC2 has been identified as part of the chromosomal passenger complex (CPC) which coordinates the chromosomal and cytoskeletal events of mitosis. Chromosomal passengers are proteins present in complexes with aurora B, inner centromeric protein (INCENP), survivin, and borealin. RCC2 has been demonstrated to be required for the recruitment of survivin and aurora B and is essential for proper chromosome segregation and the completion of cell cleavage. Loss of RCC2 inhibits spindle assembly, activates the spindle assembly checkpoint, and blocks cells in prometaphase. |
Immunogen | Epitope: between 475 and C-term |
Other Names | RCC1-like protein TD-60; TD-60; protein RCC2; epididymis secretory sperm binding protein; telophase disk protein of 60 kDa |
Gene, Accession # | Gene ID: 55920, Accession: NP_061185.1, UniProt: Q9P258 |
Catalog # | IHC-00155 |
Price | $459 |
Order / More Info | RCC2 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |