MCM7 Antibody from FORTIS LIFE SCIENCES

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Antigenic SpecificityMCM7
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatantigen affinity purified
Size10 µl
Concentration200 µg/ml
ApplicationsWB, IP
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DescriptionRabbit anti-MCM7 Antibody, Affinity Purified. The MCM (Mini-Chromosome Maintenance) complex is a key component of the pre-replication complex involved in replication licensing which restricts DNA replication to only once per cell cycle. The MCM complex is a heterohexamer of MCM2, MCM3, MCM4, MCM5, MCM6, and MCM7. MCM7 is part of the core MCM complex that includes MCM4, MCM6, and MCM7. The core complex possesses DNA helicase activity. MCM7 has been shown to interact with CDK4 and p27Kip1 to regulate cell cycle progression. MCM7 has also been shown to interact with ATR-interacting protein (ATRIP)-ATR to function as a transmitter of DNA damage signals from replication forks to S-phase checkpoint machinery.
ImmunogenEpitope: between 300 and 350
Other Nameshomolog of S. cerevisiae Cdc47; P1CDC47; protein phosphatase 1, regulatory subunit 104; PPP1R104; PNAS146; P85MCM; P1.1-MCM3; MCM2; DNA replication licensing factor MCM7; CDC47 homolog; CDC47; minichromosome maintenance deficient 7
Gene, Accession #Gene ID: 4176, Accession: NP_005907.3, UniProt: P33993
Catalog #A302-584A-T
Price$121
Order / More InfoMCM7 Antibody from FORTIS LIFE SCIENCES
Product Specific Referencesn/a
FORTIS LIFE SCIENCES
FORTIS LIFE SCIENCES
FORTIS LIFE SCIENCES
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