MCSP Antibody from FORTIS LIFE SCIENCES

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Antigenic SpecificityMCSP
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatantigen affinity purified
Size100 µl
Concentration200 µg/ml
ApplicationsWB, IP
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DescriptionRabbit anti-MCSP Antibody, Affinity Purified. Melanoma chondroitin sulfate proteoglycan (MCSP) is a cell-surface antigen expressed early in melanoma progression. It has been found to be involved in the spreading, invasion, and migration of human melanoma. MCSP influences melanoma behavior via the activation of the Cdc42 GTPase and phosphorylation of p130Cas. MCSP also activates signaling cascades involving FAK and ERK1/ERK2. In addition to its expression in melanoma cells, MCSP is also found in breast carcinomas, gliomas, neuroblastomas, and acute leukemias. MCSP is being considered as a target antigen for cancer immunotherapy.
ImmunogenEpitope: between 575 and 625
Other Namesmelanoma chondroitin sulfate proteoglycan; NG2; MSK16; melanoma-associated chondroitin sulfate proteoglycan; MCSPG; MCSP; HMW-MAA; chondroitin sulfate proteoglycan NG2; chondroitin sulfate proteoglycan 4 (melanoma-associated); chondroitin sulfate proteoglycan 4; MEL-CSPG
Gene, Accession #Gene ID: 1464, Accession: NP_001888.2, UniProt: Q6UVK1
Catalog #A302-121A
Price$433
Order / More InfoMCSP Antibody from FORTIS LIFE SCIENCES
Product Specific Referencesn/a
FORTIS LIFE SCIENCES
FORTIS LIFE SCIENCES
FORTIS LIFE SCIENCES
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