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Antigenic Specificity | CHD3 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, (presumed: rat, dog, horse, rabbit, porcine, panda, orangutan, monkey, gorilla, chimpanzee, white-tufted-ear marmoset, crab-eating macaque, naked mole rat, gray short-tailed opossum, sma |
Isotype | n/a |
Format | antigen affinity purified |
Size | 100 µl |
Concentration | 250 µg/ml |
Applications | IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-CHD3 IHC Antibody, Affinity Purified. CHD3 is a member of the CHD (chromodomain-helicase-DNA-binding) family of proteins that interacts with nucleosomes and plays a role in chromatin remodeling to modulate transcription. The members of the CHD family of proteins possess 3 common structural and functional domains: a chromodomain (chromatin organization modifier), an SNF2-like helicase/ATPase domain, and a C-terminal DNA-binding domain. CHD3 is a key component of the NuRD (nucleosomal remodeling) complex and directly interacts with histone deacetylases 1 and 2, ATR, and TRIM 27. Studies in several species suggest a role for CHD3 in the repression of developmental genes. |
Immunogen | Epitope: between 1950 and 2000 |
Other Names | Mi-2a; zinc finger helicase; zinc-finger helicase (Snf2-like); ZFH; Mi2-ALPHA; hZFH; chromodomain-helicase-DNA-binding protein 3; ATP-dependent helicase CHD3; CHD-3; mi-2 autoantigen 240 kDa protein |
Gene, Accession # | Gene ID: 1107, Accession: NP_001005273.1, UniProt: Q12873 |
Catalog # | IHC-00247 |
Price | $459 |
Order / More Info | CHD3 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |