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Antigenic Specificity | 4-1BBL/CD137L/TNFSF9 |
Clone | monoclonal |
Host Species | Recombinant Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | purified |
Size | 100 µl (10 blots) |
Concentration | 1000 µg/ml |
Applications | WB, Flow Cyt |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-4-1BBL/CD137L/TNFSF9 Recombinant Monoclonal Antibody [BLR148J]. 4-1BBL (aka CD137L or TNFSF9) is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. 4-1BBL and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells; they are also involved in promoting T lymphocyte proliferation. 4-1BBL has been shown to be required for the optimal CD8 responses in CD8 T cells. 4-1BBL is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction. [taken from NCBI Entrez Gene (Gene ID: 8744)]. |
Immunogen | Epitope: residues 71-254 (ECD) |
Other Names | homolog of mouse 4-1BB-L; tumor necrosis factor superfamily member 9; tumor necrosis factor ligand superfamily member 9; tumor necrosis factor ligand 5A; tumor necrosis factor (ligand) superfamily, member 9; receptor 4-1BB ligand; CD137L; 4-1BB-L; 4-1BBL; 4-1BB ligand; TNLG5A |
Gene, Accession # | Gene ID: 8744, Accession: NP_003802.1, UniProt: P41273 |
Catalog # | A700-148 |
Price | $306 |
Order / More Info | 4-1BBL/CD137L/TNFSF9 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |