CIP2A Antibody from FORTIS LIFE SCIENCES
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| Antigenic Specificity | CIP2A |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse, rat |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 10 µl |
| Concentration | 200 µg/ml |
| Applications | WB, IP, IHC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit anti-CIP2A Antibody, Affinity Purified. CIP2A (cancerous inhibitor of PP2A) was originally identified as p90, a cytoplasmic autoantigen found in the serum from a cancer patient. It was later described as a protein that interacted with the c-myc oncogene and functioned as an inhibitor of protein phosphatase 2A (PP2A) activity. Inhibition of PP2A phosphatase activity by CIP2A prevents c-myc phosphorylation and counteracts c-myc proteolytic degradation, thereby stabilizing c-myc and promoting cell growth and transformation. CIP2A is found to be overexpressed in some human malignancies and is thus classified as an oncogene that may be an important contributor to tumor formation. |
| Immunogen | Epitope: between 853 and 903 |
| Other Names | KIAA1524; protein CIP2A; p90; cancerous inhibitor of PP2A; cancerous inhibitor of protein phosphatase 2A; p90 autoantigen |
| Gene, Accession # | Gene ID: 57650, Accession: NP_065941.1, UniProt: Q8TCG1 |
| Catalog # | A301-454A-T |
| Price | $121 |
| Order / More Info | CIP2A Antibody from FORTIS LIFE SCIENCES |
| Product Specific References | n/a |
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