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Antigenic Specificity | CAND1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, (presumed: mouse, rat, bovine, orangutan) |
Isotype | n/a |
Format | antigen affinity purified |
Size | 10 µl |
Concentration | 1000 µg/ml |
Applications | IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-CAND1 Antibody, Affinity Purified. Cullin-associated NEDD8-dissociated protein 1 (CAND1) is a regulatory protein that interferes with the assembly of the SCF (SKP1-CUL1-F-box protein) ubiquitin ligase complex and thereby down-regulates ubiquitination of target proteins. CAND1 prevents neddylation of CUL1 by physically blocking access to the neddylation site and disrupts interactions between CUL1 and SKP1A and between CUL1 and F-box proteins. CAND1 also binds TATA binding protein and enhances transcription from various promoters [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/ Q86VP6]. |
Immunogen | Epitope: between 600 and 650 |
Other Names | TIP120A; Cullin-associated and neddylation-dissociated protein 1; cullin-associated NEDD8-dissociated protein 1; p120 CAND1; TBP-interacting protein 120A; TBP-interacting protein of 120 kDa A; TIP120 |
Gene, Accession # | Gene ID: 55832, Accession: NP_060918.2, UniProt: Q86VP6 |
Catalog # | A302-900A-T |
Price | $121 |
Order / More Info | CAND1 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |