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Antigenic Specificity | IDE |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, (presumed: mouse, rat, bovine) |
Isotype | n/a |
Format | antigen affinity purified |
Size | 10 µl |
Concentration | 1000 µg/ml |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-IDE Antibody, Affinity Purified. Insulin-degrading enzyme (IDE) is a metalloendopeptidase that plays a primary role in the regulated degradation of insulin. In the cell, IDE is found mostly in the soluble cytosolic fraction, and small amounts exist in the plasma membrane, endosomes, and peroxisomes; however the highest relative concentration is found in the peroxisomes. IDE is proposed to be a multifunctional enzyme since it is also present in non-insulin sensitive cells. Other substrates of IDE include glucagon, IGF-II, atrial natriuretic factor, and TGF-alpha. |
Immunogen | Epitope: between 275 and 326 |
Other Names | INSULYSIN; insulin protease; Abeta-degrading protease; insulin-degrading enzyme; insulinase |
Gene, Accession # | Gene ID: 3416, Accession: NP_004960.1, UniProt: P14735 |
Catalog # | A301-906A-T |
Price | $121 |
Order / More Info | IDE Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |