Ric-8A Antibody from FORTIS LIFE SCIENCES

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Antigenic SpecificityRic-8A
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman
Isotypen/a
Formatantigen affinity purified
Size100 µl
Concentration1000 µg/ml
ApplicationsIP
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DescriptionRabbit anti-Ric-8A Antibody, Affinity Purified. RIC8 guanine nucleotide exchange factor A (Ric-8A), also known as Synmebryn-A, is a guanine nucleotide exchange factor (GEF), which can activate some, but not all, G-alpha proteins. It is able to activate GNAI1, GNAO1 and GNAQ, but not GNAS by exchanging bound GDP for free GTP. Ric-8A is involved in regulation of microtubule pulling forces during mitotic movement of chromosomes by stimulating G(i)-alpha protein, possibly leading to release G(i)-alpha-GTP and NuMA proteins from the NuMA-GPSM2-G(i)-alpha-GDP complex (By similarity). It also acts as an activator for G(q)-alpha (GNAQ) protein by enhancing the G(q)-coupled receptor-mediated ERK activation [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9NPQ8].
ImmunogenEpitope: between 1 and 50
Other NamesProtein Ric-8A; resistance to inhibitors of cholinesterase 8 homolog A; RIC8; synembryn-A
Gene, Accession #Gene ID: 60626, Accession: NP_068751.4, UniProt: Q9NPQ8
Catalog #A304-571A
Price$433
Order / More InfoRic-8A Antibody from FORTIS LIFE SCIENCES
Product Specific Referencesn/a
FORTIS LIFE SCIENCES
FORTIS LIFE SCIENCES
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