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Antigenic Specificity | p150glued |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | antigen affinity purified |
Size | 10 µl |
Concentration | 1000 µg/ml |
Applications | WB, IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-p150glued Antibody, Affinity Purified. p150glued is the largest subunit of dynactin, a macromolecular complex consisting of 10 subunits ranging in size from 22 to 150 kD. Dynactin binds to both microtubules and cytoplasmic dynein. Dynactin is involved in a diverse array of cellular functions, including ER-to-Golgi transport, the centripetal movement of lysosomes and endosomes, spindle formation, chromosome movement, nuclear positioning, and axonogenesis. The p150glued subunit interacts with dynein intermediate chain by its domains directly binding to dynein and binds to microtubules via a highly conserved glycine-rich cytoskeleton-associated protein (CAP-Gly) domain in its N-terminus [taken from NCBI Entrez Gene (Gene ID: 1639)]. |
Immunogen | Epitope: between 1228 and 1278 |
Other Names | DAP-150; p150-glued; P135; dynactin subunit 1; DP-150; 150 kDa dynein-associated polypeptide; dynactin 1 (p150, glued homolog, Drosophila) |
Gene, Accession # | Gene ID: 1639, Accession: NP_004073.2, UniProt: Q14203 |
Catalog # | A303-072A-T |
Price | $121 |
Order / More Info | p150glued Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |