COP1/RFWD2 Antibody from FORTIS LIFE SCIENCES
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| Antigenic Specificity | COP1/RFWD2 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, mouse |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 10 µl |
| Concentration | 1000 µg/ml |
| Applications | WB, IP |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit anti-COP1/RFWD2 Antibody, Affinity Purified. Constitutive photomorphogenic protein 1 (COP1) has been characterized in plants as a RING-finger-containing protein that functions to repress plant photomorphogenesis. In mammals, COP1 has been identified as an E3 ubiquitin ligase that negatively regulates p53 protein levels in unstressed cells. In response to DNA damage COP1 is phosphorylated by the ataxia telangiectasia mutated (ATM) protein kinase and is rapidly degraded releasing p53 to exert its tumor suppressor activities. |
| Immunogen | Epitope: between 1 and 50 |
| Other Names | RFWD2; RING-type E3 ubiquitin transferase RFWD2; RNF200; RING finger protein 200; RING finger and WD repeat domain protein 2; ring finger and WD repeat domain 2, E3 ubiquitin protein ligase; hCOP1; E3 ubiquitin-protein ligase RFWD2; E3 ubiquitin-protein ligase COP1; constitutive photomorphogenic protein 1; constitutive photomorphogenesis protein 1 homolog; putative ubiquitin ligase COP1 |
| Gene, Accession # | Gene ID: 64326, Accession: NP_071902.2, UniProt: Q8NHY2 |
| Catalog # | A300-894A-T |
| Price | $121 |
| Order / More Info | COP1/RFWD2 Antibody from FORTIS LIFE SCIENCES |
| Product Specific References | n/a |
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