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Antigenic Specificity | LIS-1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat, (presumed: zebrafish, Xenopus laevis, Xenopus tropicalis, chicken, bovine, porcine, cat, orangutan, chimpanzee) |
Isotype | n/a |
Format | antigen affinity purified |
Size | 100 µl |
Concentration | 1000 µg/ml |
Applications | WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-LIS-1 Antibody, Affinity Purified. Lissencephaly-1 protein (LIS-1) was identified as a gene associated with Miller-Dieker lissencephaly syndrome, an autosomal dominant disorder characterized by microcephaly along with anomalies of the kidney, heart, and gastrointestinal tract. LIS-1 is the non-catalytic alpha subunit of the intracellular isoform of platelet-activating factor acetylhydrolase. LIS-1 plays an important role in neuron migration during brain development and fibroblast migration during wound healing. Its role in migration is related to its function in regulating dynein-mediated microtubule sliding. |
Immunogen | Epitope: between 1 and 50 |
Other Names | MDCR; PAFAH; platelet-activating factor acetylhydrolase, isoform Ib, alpha subunit (45kD); platelet-activating factor acetylhydrolase IB subunit alpha; platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa); PAF-AH alpha; PAFAH alpha; PAF-AH 45 kDa subunit; platelet-activating factor acetylhydrolase, isoform Ib, subunit 1 (45kDa); PAF acetylhydrolase 45 kDa subunit; MDS; Lissencephaly-1 protein; lissencephaly 1 protein; LIS2; LIS-1; LIS1; NudF |
Gene, Accession # | Gene ID: 5048, Accession: NP_000421.1, UniProt: P43034 |
Catalog # | A300-409A |
Price | $433 |
Order / More Info | LIS-1 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |