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Antigenic Specificity | TAF1 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 10 µl |
Concentration | 1000 µg/ml |
Applications | WB, IP, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-TAF1 Antibody, Affinity Purified. Transcription initiation factor TFIID subunit 1 (TAF1) is the largest component and core scaffold of the TFIID basal transcription factor complex. TAF1 contains novel N- and C-terminal Ser/Thr kinase domains which can autophosphorylate or transphosphorylate other transcription factors. TAF1 phosphorylates TP53 on 'Thr-55' which leads to MDM2-mediated degradation of TP53. It also phosphorylates GTF2A1 and GTF2F1 on Ser residues. TAF1 possesses DNA-binding activity and is essential for progression of the G1 phase of the cell cycle [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P21675]. |
Immunogen | Epitope: between 1750 and 1800 |
Other Names | Transcription initiation factor TFIID 250 kDa subunit; TAF(II)250; TAF1 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 250kDa; TAF2A; TAFII250; TAFII-250; OF; transcription factor TFIID p250 polypeptide; N-TAF1; transcription initiation factor TFIID subunit 1; XDP; TBP-associated factor 250 kDa; cell cycle gene 1 protein; BA2R; P250; CCGS; cell cycle, G1 phase defect; complementation of cell cycle block, G1-to-S; DYT3; DYT3/TAF1; KAT4; MRXS33; NSCL2; CCG1 |
Gene, Accession # | Gene ID: 6872, UniProt: P21675 |
Catalog # | A303-504A-T |
Price | $121 |
Order / More Info | TAF1 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |