Astrin/MAP126 Antibody from FORTIS LIFE SCIENCES
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| Antigenic Specificity | Astrin/MAP126 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 100 µl |
| Concentration | 1000 µg/ml |
| Applications | IP |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit anti-Astrin/MAP126 Antibody, Affinity Purified. Astrin/MAP126 has been identified as a mitotic spindle-associated protein essential for centrosome integrity and the progression through mitosis. Astrin/MAP126 interacts with Ninein and Aurora-A at the centrosome. Ninein, but not Aurora-A, appears to be required for proper localization of Astrin/MAP126 to the centrosome during S and G2 phase. A pool of Astrin/MAP126 also localizes to the outer kinetochore where it plays an essential role in chromatid adhesion and chromosome congression and segregation. The localization of Astrin/MAP126 to the spindle pole and kinetochore has been shown to be dependent on its phosphorylation by glycogen synthase kinase 3beta (GSK3beta). |
| Immunogen | Epitope: between 1 and 50 |
| Other Names | hMAP126; sperm-associated antigen 5; Mitotic spindle-associated protein p126; mitotic spindle coiled-coil related protein; DEEPEST; astrin; mitotic spindle associated protein p126; MAP126 |
| Gene, Accession # | Gene ID: 10615, Accession: NP_006452.3, UniProt: Q96R06 |
| Catalog # | A301-511A |
| Price | $433 |
| Order / More Info | Astrin/MAP126 Antibody from FORTIS LIFE SCIENCES |
| Product Specific References | n/a |
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