RNF20 Antibody from FORTIS LIFE SCIENCES
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| Antigenic Specificity | RNF20 |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 10 µl |
| Concentration | 250 µg/ml |
| Applications | IHC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit anti-RNF20 IHC Antibody, Affinity Purified. The conjugation of ubiquitin to proteins is an important means to regulate protein activity for many cellular processes. Targeting of proteins by ubiquitination occurs in three main steps that involve the activation of ubiquitin by E1 enzymes, the carrying of ubiquitin to the target protein by E2 enzymes, and the ligation of ubiquitin to the target protein by E3 enzymes. Ring finger protein 20 (RNF20) is a member of the RING type E3 ubiquitin ligases. RNF20 forms a complex with RNF40 to carry out H2B monoubiquitination in association with hPAF and the UbcH6 ubiquitin E2-conjugating enzyme. H2B monoubiquitination by RNF40/RNF20 has been shown to be associated with increased H3 methylation and gene transcription. |
| Immunogen | Epitope: between 125 and 175 |
| Other Names | hBRE1; BRE1; RING-type E3 ubiquitin transferase BRE1A; RING finger protein 20; homolog of S. cerevisiae BRE1; BRE1-A; BRE1A; BRE1 E3 ubiquitin ligase homolog; E3 ubiquitin-protein ligase BRE1A |
| Gene, Accession # | Gene ID: 56254, Accession: NP_062538.5, UniProt: Q5VTR2 |
| Catalog # | IHC-00100-T |
| Price | $121 |
| Order / More Info | RNF20 Antibody from FORTIS LIFE SCIENCES |
| Product Specific References | n/a |
FORTIS LIFE SCIENCES
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