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Antigenic Specificity | STAT2 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human |
Isotype | n/a |
Format | antigen affinity purified |
Size | 100 µl |
Concentration | 200 µg/ml |
Applications | WB, IP, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-STAT2 Antibody, Affinity Purified. Signal transducer and activator of transcription 2 (STAT2) is a signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with ISGF3G/IRF-9 to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P52630]. |
Immunogen | Epitope: between 725 and 775 |
Other Names | IMD44; signal transducer and activator of transcription 2; STAT113; signal transducer and activator of transcription 2, 113kDa; ISGF-3; interferon alpha induced transcriptional activator; P113 |
Gene, Accession # | Gene ID: 6773, Accession: NP_005410.1, UniProt: P52630 |
Catalog # | A303-511A |
Price | $433 |
Order / More Info | STAT2 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |