TfR Antibody from FORTIS LIFE SCIENCES
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| Antigenic Specificity | TfR |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human, (presumed: dog, horse, orangutan) |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 10 µl |
| Concentration | 1000 µg/ml |
| Applications | WB |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit anti-TfR Antibody, Affinity Purified. Cellular uptake of iron occurs via receptor-mediated endocytosis of ligand-occupied transferrin receptor (TR) into specialized endosomes. Endosomal acidification leads to iron release. The apotransferrin-receptor complex is then recycled to the cell surface with a return to neutral pH and the concomitant loss of affinity of apotransferrin for its receptor. Transferrin receptor is necessary for development of erythrocytes and the nervous system (By similarity). A second ligand, the heditary hemochromatosis protein HFE, competes for binding with transferrin for an overlapping C-terminal binding site [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/P02786]. |
| Immunogen | Epitope: between 125 and 175 |
| Other Names | CD antigen CD71; TFR1; transferrin receptor protein 1; TRFR; TR; T9; p90; CD71; IMD46; TFR |
| Gene, Accession # | Gene ID: 7037, Accession: NP_003225.2, UniProt: P02786 |
| Catalog # | A304-381A-T |
| Price | $121 |
| Order / More Info | TfR Antibody from FORTIS LIFE SCIENCES |
| Product Specific References | n/a |
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