Rictor Antibody from FORTIS LIFE SCIENCES
Search, find, compare suppliers for anti-Rictor antibody, protein, ELISA kits.
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| Antigenic Specificity | Rictor |
| Clone | polyclonal |
| Host Species | Rabbit |
| Reactive Species | human |
| Isotype | n/a |
| Format | antigen affinity purified |
| Size | 10 µl |
| Concentration | 1000 µg/ml |
| Applications | IP, IHC |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Rabbit anti-Rictor Antibody, Affinity Purified. Rictor is a subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 'Ser-473' phosphorylation, which may facilitate the phosphorylation of the activation loop of AKT1 on 'Thr-308' by PDK1 which is a prerequisite for full activation. mTORC2 regulates the phosphorylation of SGK1 at 'Ser-422'. mTORC2 also modulates the phosphorylation of PRKCA on 'Ser-657'. Plays an essential role in embryonic growth and development [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q6R327]. |
| Immunogen | Epitope: between 1 and 50 |
| Other Names | hAVO3; TORC2-specific protein AVO3; rapamycin-insensitive companion of mTOR; PIA; AVO3 homolog; AVO3; pianissimo |
| Gene, Accession # | Gene ID: 253260, Accession: NP_689969.2, UniProt: Q6R327 |
| Catalog # | A304-329A-T |
| Price | $121 |
| Order / More Info | Rictor Antibody from FORTIS LIFE SCIENCES |
| Product Specific References | n/a |
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