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Antigenic Specificity | SUZ12 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | antigen affinity purified |
Size | 100 µl |
Concentration | 200 µg/ml |
Applications | WB, IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-SUZ12 Antibody, Affinity Purified. SUZ12 (suppressor of zeste 12) is the human homolog of the drosophila SUZ12 gene. SUZ12 is a Polycomb group (PcG) protein and a component of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' and 'Lys-27' of histone H3, leading to transcriptional repression of the affected target gene. A chromosomal aberration, t(7;17)(p15;q21), involving SUZ12 and JAZF1 may be a cause of endometrial stromal tumors. The translocation generates the JAZF1-SUZ12 oncogene consisting of the N-terminus part of JAZF1 and the C-terminus part of SUZ12. It is frequently found in all cases of endometrial stromal tumors, except in endometrial stromal sarcomas, where it is rarer [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q15022]. |
Immunogen | Epitope: between 689 and 739 |
Other Names | CHET9; suppressor of zeste 12 protein homolog; polycomb protein SUZ12; joined to JAZF1 protein; chromatin precipitated E2F target 9 protein; chET 9 protein; JJAZ1 |
Gene, Accession # | Gene ID: 23512, Accession: NP_056170.2, UniProt: Q15022 |
Catalog # | A302-407A |
Price | $433 |
Order / More Info | SUZ12 Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |