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Antigenic Specificity | RAF1/c-Raf |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, (presumed: rat, bovine, orangutan) |
Isotype | n/a |
Format | antigen affinity purified |
Size | 100 µl |
Concentration | 200 µg/ml |
Applications | WB, IP |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-RAF1/c-Raf Antibody, Affinity Purified. RAF1 is a mitogen activated kinase kinase kinase (MAPKKK). In response to extracellular signals, RAF1 phosphorylates the MEK1 and MEK2 MAP kinase kinases. MEK1 and MEK2 subsequently phosphorylate and activate the ERK1 and ERK2 MAP kinases to exert pleiotropic effects on cellular functions such as growth, division, differentiation, motility, and apoptosis. RAF1 associates with the Ras family of membrane GTPases and functions downstream of Ras activity. |
Immunogen | Epitope: between 598 and 648 |
Other Names | C-Raf proto-oncogene, serine/threonine kinase; v-raf-1 murine leukemia viral oncogene homolog 1; Raf-1; RAF proto-oncogene serine/threonine-protein kinase; raf proto-oncogene serine/threonine protein kinase; proto-oncogene c-RAF; NS5; v-raf-1 murine leukemia viral oncogene-like protein 1; c-Raf; CRAF; CMD1NN; Oncogene RAF1 |
Gene, Accession # | Gene ID: 5894, Accession: NP_002871.1, UniProt: P04049 |
Catalog # | A301-519A |
Price | $433 |
Order / More Info | RAF1/c-Raf Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |