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Antigenic Specificity | PELP1/MNAR |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse |
Isotype | n/a |
Format | antigen affinity purified |
Size | 100 µl |
Concentration | 1000 µg/ml |
Applications | WB, IP, IHC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit anti-PELP1/MNAR Antibody, Affinity Purified. PELP1/MNAR was identified as an SH2 domain interacting protein that interacts with Lck, c-Src, and other members of the Src kinase family. PELP1/MNAR appears to function as a general coregulator and interacts with multiple nuclear receptors and transcription factors. PELP1/MNAR has also been shown to participate in nongenomic signaling via an association with a multiprotein complex, the ``signalsome'' involving ERalpha, Src kinase, PI3K, SHC, and G-proteins. As a transcriptional coregulator and signaling protein, PELP/MNAR mediates a variety of cellular functions such as cell proliferation, apoptosis, differentiation, oncogenesis and metastasis. |
Immunogen | Epitope: between 1000 and 1050 |
Other Names | MNAR; modulator of non-genomic activity of estrogen receptor; P160; proline and glutamic acid rich nuclear protein; proline-, glutamic acid- and leucine-rich protein 1; transcription factor HMX3 |
Gene, Accession # | Gene ID: 27043, Accession: NP_055204.4, UniProt: Q8IZL8 |
Catalog # | A300-180A |
Price | $433 |
Order / More Info | PELP1/MNAR Antibody from FORTIS LIFE SCIENCES |
Product Specific References | n/a |