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Antigenic Specificity | C1q |
Clone | JL-1 |
Host Species | Mouse |
Reactive Species | human, mouse, rat |
Isotype | IgG2b |
Format | Protein G purified |
Size | 50 µg |
Concentration | 100 µg/ml |
Applications | Depletion, ELISA, ICC/IF, IHC-Fr, PLA, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse anti-C1q monoclonal antibody [JL-1]. The monoclonal antibody JL-1 is reactive with the collagen-like region (CLR) only, which is the same region to which autoantibodies in mice and humans are binding. Anti-C1q autoantibodies deposit in glomeruli together with C1q but induce overt renal disease only in the context of glomerular immune complex disease. This provides an explanation why anti-C1q antibodies are especially pathogenic in patients with SLE. |
Immunogen | Purified mouse C1q |
Other Names | complement component 1, q subcomponent, alpha polypeptide , complement component 1, q subcomponent, beta polypeptide , complement component 1, q subcomponent, C chain , AI255395 , Adic , C1q , Adia , AI385742 , Adib , C1qg , Ciqc |
Gene, Accession # | Gene ID: 12259, UniProt: P98086|Q02105|P14106 |
Catalog # | GTX54404 |
Price | $399 |
Order / More Info | C1q Antibody from GENETEX INC. |
Product Specific References | PubMed: 32894219, 35690144, 36600274 |