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Antigenic Specificity | Human HLA-DR |
Clone | L243 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG2a |
Format | Protein A/G purified, low endotoxin |
Size | 50mg |
Concentration | 1.0 mg/ml |
Applications | Western Blot, Blocking, Flow Cytometry, Immunoprecipitation, CyTOF, IHC (Frozen). RUO |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Anti-HLA-DR In Vivo Antibody - Low Endotoxin (L243) recognizes/reacts with the HLA-DR antigen, a member of MHC class II molecules. It does not cross-react with HLA-DP and HLA-DQ. HLA-DR is a heterodimeric cell surface glycoprotein comprised of a 36 kD (heavy) chain & a 27 kD (light) chain. It is expressed on B cells, activated T cells, monocytes/macrophages, and dendritic cells. HLA-DR is critical for efficient peptide presentation to CD4+ T cells. Clone L243 binds a conformational epitope on HLA-DRalpha which depends on the correct folding of the Aβ heterodimer. |
Immunogen | n/a |
Other Names | Major Histocompatibility Class II, MHC class II, HLA-DR Monomorphic |
Gene, Accession # | n/a |
Catalog # | ICH1026-50mg |
Price | $1775 |
Order / More Info | Human HLA-DR Antibody from ICHORBIO |
Product Specific References | WNT4 promotes macrophage polarization via granulosa cell M-CSF and reduces granulosa cell apoptosis in endometriosis: https://assets.researchsquare.com/files/rs-1808461/v1/f16c4b29-5d6c-495e-87dc-aca6693365d2.pdf?c=1657848557 |
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