Mouse IL-1b Antibody from ICHORBIO

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Antigenic SpecificityMouse IL-1b
CloneB122
Host SpeciesArmenian Hamster
Reactive Speciesmouse
IsotypeIgG
FormatProtein A/G purified, low endotoxin
Size50mg
Concentration1.0 mg/ml
ApplicationsNeutralization, Immunoprecipitation, Western Blot, ELISA. RUO
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DescriptionSpecificity: Anti-IL-1b In Vivo Antibody - Low Endotoxin (B122) recognizes Mouse IL-1B. Interleukin 1 beta (IL1 beta) is a proinflammatory cytokine belonging to IL1 family that is synthesized as a precursor. The IL1 beta precursor form is not biologically active. It is expressed mainly by stimulated macrophages and monocytes. IL1 beta is known to be a mediator in inflammatory response and to be involved in a variety of cellular activities, proliferation, differentiation and apoptosis. It has been recently found that IL1 beta is a major cause of severe inflammation in the mouse model of Crohns disease which makes IL1 beta an important target for this disease. The B122 antibody has been reported to neutralize the bioactivity of natural or recombinant IL-1β.
ImmunogenE. coli -expressed, recombinant mouse IL-1β
Other NamesInterleukin-1 beta, IL-1B
Gene, Accession #UniProt: P10749
Catalog #ICH1100-50mg
Price$1775
Order / More InfoMouse IL-1b Antibody from ICHORBIO
Product Specific Referencesn/a
ICHORBIO
ICHORBIO
ICHORBIO
Boston House, Grove Business Park
Downsview Road
Wantage OX12 9FF ENGLAND

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Wayne, PA 19087
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