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Antigenic Specificity | Mouse IL-1b |
Clone | B122 |
Host Species | Armenian Hamster |
Reactive Species | mouse |
Isotype | IgG |
Format | Protein A/G purified, low endotoxin |
Size | 50mg |
Concentration | 1.0 mg/ml |
Applications | Neutralization, Immunoprecipitation, Western Blot, ELISA. RUO |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Anti-IL-1b In Vivo Antibody - Low Endotoxin (B122) recognizes Mouse IL-1B. Interleukin 1 beta (IL1 beta) is a proinflammatory cytokine belonging to IL1 family that is synthesized as a precursor. The IL1 beta precursor form is not biologically active. It is expressed mainly by stimulated macrophages and monocytes. IL1 beta is known to be a mediator in inflammatory response and to be involved in a variety of cellular activities, proliferation, differentiation and apoptosis. It has been recently found that IL1 beta is a major cause of severe inflammation in the mouse model of Crohns disease which makes IL1 beta an important target for this disease. The B122 antibody has been reported to neutralize the bioactivity of natural or recombinant IL-1β. |
Immunogen | E. coli -expressed, recombinant mouse IL-1β |
Other Names | Interleukin-1 beta, IL-1B |
Gene, Accession # | UniProt: P10749 |
Catalog # | ICH1100-50mg |
Price | $1775 |
Order / More Info | Mouse IL-1b Antibody from ICHORBIO |
Product Specific References | n/a |
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