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Antigenic Specificity | Mouse TNF alpha |
Clone | TN3-19.12 |
Host Species | Armenian Hamster |
Reactive Species | mouse |
Isotype | IgG |
Format | Protein A/G purified, low endotoxin |
Size | 100mg |
Concentration | 1.0 mg/ml |
Applications | Immunoprecipitation, Western Blot, Functional Assays, Flow Cytometry, Blocking. RUO |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Specificity: Anti-TNF alpha In Vivo Antibody - Low Endotoxin (TN3-19.12) recognizes Mouse TNFa. The tumor necrosis factor (TNF-alpha) is a multifaceted polypeptide cytokine known as a mediator of inflammation and immunity. It may mediate some of the significant changes in cellular homeostasis which accompany the invasion of the mammalian host by viruses, bacteria, and parasites. TNF-alpha is an acute phase protein which initiates a cascade of cytokines and increases vascular permeability, thereby recruiting macrophage and neutrophils to a site of infection. TNF-alpha secreted by the macrophage causes blood clotting which serves to contain the infection. TNF-alpha has been detected in synovial fluid of patients with rheumatoid arthritis. Clone TN3-19.12 antibody can neutralize the bioactivity of natural or recombinant TNF-alpha |
Immunogen | Recombinant mouse TNFalpha |
Other Names | Cachectin, TNFa, Tumor necrosis factor ligand superfamily member 2, Tnfsf2 |
Gene, Accession # | UniProt: P06804 |
Catalog # | ICH1136-100mg |
Price | $2600 |
Order / More Info | Mouse TNF alpha Antibody from ICHORBIO |
Product Specific References | n/a |
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