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Antigenic Specificity | CD29, Human |
Clone | REA1060 |
Host Species | Recombinant Human |
Reactive Species | human |
Isotype | IgG1 |
Format | Vio Bright B515 conjugate |
Size | 100 tests in 200 µL |
Concentration | 1:50 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD29 Antibody, anti-human, Vio® Bright B515, REAfinity™. Clone REA1060 recognizes the human CD29 antigen, a 130 kDa single-pass type I membrane protein. CD29 is also known as integrin β1 or GPIIa. It forms heterodimers with integrins α1-11 and αV to form functional integrin receptors which bind several cell surface and extracellular molecules such as collagen, fibronectin, laminin, VCAM1, cytotactin, osteopontin, epiligrin, thrombospondin, etc. The cytoplasmic domain of CD29 can interact with cytoskeletal proteins and signaling molecules. In humans, CD29 can be found in four different isoforms (β1A, β1B, β1C, β1D). | Additional information: Clone REA1060 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | ITGB1, FNRB, GPIIa, MDF2, MSK12, VLA-BETA, VLAB |
Gene, Accession # | Gene ID: 3688 |
Catalog # | 130-118-126 |
Price | $470 |
Order / More Info | CD29, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Altruda, F. et al. (1990) A human integrin beta 1 subunit with a unique cytoplasmic domain generated by alternative mRNA processing. Gene 95: 261-266. | Shih, D. T. et al. (1993) Structure/function analysis of the integrin beta 1 subunit by epitope mapping. J. Cell Biol. 122 (6): 1361-1371. | Brakebusch, C. et al. (1997) Genetic analysis of beta1 integrin function: confirmed, new and revised roles for a crucial family of cell adhesion molecules. J. Cell. Sci. 110: 2895-2904. |