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Antigenic Specificity | CD352 (NTB-A), Mouse |
Clone | 13G3 |
Host Species | Mouse |
Reactive Species | mouse |
Isotype | IgG2aκ |
Format | allophycocyanin (APC) conjugate |
Size | 30 µg in 1 mL |
Concentration | 1:10 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD352 (NTB-A) Antibody, anti-mouse, APC. Clone 13G3 recognizes the mouse CD352 antigen, a single-pass type I membrane protein, also known as SLAM family member 6 (SLAM6) or NK, T, and B cell antigen (NTB-A) belonging to the CD2 subfamily of the immunoglobulin superfamily. It is expressed on NK, T, and B cells. It undergoes tyrosine phosphorylation and associates with the Src homology 2 domain-containing protein (SH2D1A) as well as with SH2 domain-containing phosphatases. CD352 plays a role in NK cell cytotoxicity and T cell cytokine responses. It controls neutrophil functions and serves as a regulator of both innate and adaptive immune responses. |
Immunogen | n/a |
Other Names | SLAM family receptor, SLAMF6, SLAM F6, LY108, Lymphocyte antigen 108, SLAM family member 6 |
Gene, Accession # | Gene ID: 30925 |
Catalog # | 130-109-861 |
Price | $88 |
Order / More Info | CD352 (NTB-A), Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Howie, D. et al. (2005) Cutting edge: the SLAM family receptor Ly108 controls T cell and neutrophil functions. J Immunol 174 (10): 5931-5935. | Griewank, K. et al. (2007) Homotypic interactions mediated by Slamf1 and Slamf6 receptors control NKT cell lineage development. Immunity 27 (5): 751-762. | Peck, S. R. et al. (2000) Ly108: a new member of the mouse CD2 family of cell surface proteins. Immunogenetics 52 (1-2): 63-72. |