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Antigenic Specificity | TCRα/β, Human |
Clone | REA652 |
Host Species | Recombinant Human |
Reactive Species | human |
Isotype | IgG1 |
Format | fluorescein (FITC) conjugate |
Size | 100 tests in 200 µL |
Concentration | 1:50 |
Applications | Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TCRα/β Antibody, anti-human, FITC, REAfinity™. Clone REA652 recognizes the human α/β T cell receptor (TCR). The T cell receptor is a heterodimer composed of two transmembrane glycoprotein chains, α and β. In 95% of T cells the TCR consists of an α and β chain, whereas in 5% of T cells it has γ and δ chains. α and β chains are members of the Ig superfamily and consist of a constant and a polymorphic variable region. The variable region of the TCRα/β is involved in recognition of antigenic peptides presented by the MHC complex of antigen-presenting cells. | Additional information: Clone REA652 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | TCR a/b, IMD7, TCRA, TRAC, TRA, TRB |
Gene, Accession # | Gene ID: 6955, 6957 |
Catalog # | 130-113-538 |
Price | $275 |
Order / More Info | TCRα/β, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Brenner, M. B. et al. (1986) Identification of a putative second T-cell receptor. Nature 322 (6075): 145-149. | Call, M. E. et al. (2002) The organizing principle in the formation of the T cell receptor-CD3 complex. Cell 111 (7): 967-979. | Oettgen, H. C. et al. (1984) Characterization of the two heavy chains of the T3 complex on the surface of human T lymphocytes. J. Biol. Chem. 259 (19): 12039-12048. |