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Antigenic Specificity | TCR Vβ10, Mouse |
Clone | REA651 |
Host Species | Recombinant Human |
Reactive Species | mouse |
Isotype | IgG1 |
Format | PE-Vio 770 conjugate |
Size | 30 µg in 1 mL |
Concentration | 1:10 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TCR Vβ10 Antibody, anti-mouse, PE-Vio® 770, REAfinity™. Clone REA651 recognizes the mouse V beta 10 T cell receptor (TCR Vβ10). The T cell receptor is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a disulfide-linked membrane-anchored heterodimeric glycoprotein normally consisting of the highly variable alpha and beta chains expressed as part of a complex with the invariant CD3 chain molecules. The α and β TCR chains are composed of constant and variable regions, each encoded by distinct gene segments. TCR Vβ10 is a variant of the TCR β chain and is expressed on T cells having the a haplotype, but not with the b and c haplotype of the TCRβ gene complex. | Additional information: Clone REA651 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | TCR Vb10, Gm17526 |
Gene, Accession # | Gene ID: 100124670 |
Catalog # | 130-109-938 |
Price | $167 |
Order / More Info | TCR Vβ10, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Bour, H. et al. (1999) Dramatic influence of V beta gene polymorphism on an antigen-specific CD8+ T cell response in vivo. J Immunol 162 (8): 4647-4656. | Brenden, N. et al. (1999) Differential MHC expression requirements for positive selection of separate TCR Vb families. Immunogenetics 49 (1): 1-6. | Deepe, G. S. Jr. et al. (2002) Discordance between T-cell receptor expression and effector function in mice infected with Histoplasma capsulatum. Infect. Immun. 70 (3): 1648-1652. |