TCR Vβ10, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityTCR Vβ10, Mouse
CloneREA651
Host SpeciesRecombinant Human
Reactive Speciesmouse
IsotypeIgG1
FormatPE-Vio 770 conjugate
Size30 µg in 1 mL
Concentration1:10
ApplicationsFlow cytometry
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DescriptionTCR Vβ10 Antibody, anti-mouse, PE-Vio® 770, REAfinity™. Clone REA651 recognizes the mouse V beta 10 T cell receptor (TCR Vβ10). The T cell receptor is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a disulfide-linked membrane-anchored heterodimeric glycoprotein normally consisting of the highly variable alpha and beta chains expressed as part of a complex with the invariant CD3 chain molecules. The α and β TCR chains are composed of constant and variable regions, each encoded by distinct gene segments. TCR Vβ10 is a variant of the TCR β chain and is expressed on T cells having the a haplotype, but not with the b and c haplotype of the TCRβ gene complex. | Additional information: Clone REA651 displays negligible binding to Fc receptors.
Immunogenn/a
Other NamesTCR Vb10, Gm17526
Gene, Accession #Gene ID: 100124670
Catalog #130-109-938
Price$167
Order / More InfoTCR Vβ10, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesBour, H. et al. (1999) Dramatic influence of V beta gene polymorphism on an antigen-specific CD8+ T cell response in vivo. J Immunol 162 (8): 4647-4656. | Brenden, N. et al. (1999) Differential MHC expression requirements for positive selection of separate TCR Vb families. Immunogenetics 49 (1): 1-6. | Deepe, G. S. Jr. et al. (2002) Discordance between T-cell receptor expression and effector function in mice infected with Histoplasma capsulatum. Infect. Immun. 70 (3): 1648-1652.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

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