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Antigenic Specificity | CD4, Human |
Clone | REA623 |
Host Species | Recombinant Human |
Reactive Species | human |
Isotype | IgG1 |
Format | phycoerythrin (PE) conjugate |
Size | 30 tests in 60 µL |
Concentration | 1:50 |
Applications | Flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD4 Antibody, anti-human, PE, REAfinity™. Clone REA623 recognizes the human CD4 antigen, a 55 kDa single-pass type I membrane protein, also known as T4/Leu-3. CD4 is highly expressed on T helper cells and at a lower level on monocytes and dendritic cells. It is involved in the recognition of MHC class II/peptide complexes by the TCR heterodimers and is the receptor for the human immunodeficiency virus (HIV). | Additional information: Clone REA623 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | T4, Leu-3, CD4mut |
Gene, Accession # | Gene ID: 920 |
Catalog # | 130-113-787 |
Price | $119 |
Order / More Info | CD4, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Tebas, P. et al. (2014) Gene editing of CCR5 in autologous CD4 T cells of persons infected with HIV. N. Engl. J. Med. 370 (10): 901-910. | Maddon, P. J. et al. (1985) The isolation and nucleotide sequence of a cDNA encoding the T cell surface protein T4: a new member of the immunoglobulin gene family. Cell 42 (1): 93-104. | Barclay, A. N. et al. (1993) CD4 and the immunoglobulin superfamily. Philos. Trans. R. Soc. Lond., B, Biol. Sci. 342 (1299): 7-12. |