CD370 (CLEC9A), Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | CD370 (CLEC9A), Mouse |
| Clone | 7H11 |
| Host Species | Rat |
| Reactive Species | mouse |
| Isotype | IgG1κ |
| Format | Vio Bright FITC conjugate |
| Size | 30 µg in 200 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | CD370 (CLEC9A) Antibody, anti-mouse, Vio® Bright FITC. Clone 7H11 recognizes CD370 C-type lectin 9A (CLEC9A), also known as DC NK lectin group receptor-1 (DNGR-1). It is a protein of 264 amino acids expressed at high level on CD8a+ dendritic cells and at lower level on mPDCA-1+ plasmacytoid dendritic cells. CD370 (CLEC9A) recognizes necrotic cell associated epitopes and plays an important role in crosspresentation of dead cell derived antigens. |
| Immunogen | n/a |
| Other Names | DNGR-1 |
| Gene, Accession # | Gene ID: 232414 |
| Catalog # | 130-118-848 |
| Price | $198 |
| Order / More Info | CD370 (CLEC9A), Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Sancho, D. et al. (2008) Tumor therapy in mice via antigen targeting to a novel, DC-restricted C-type lectin. J. Clin. Invest. 118 (6): 2098-2110. | Sancho, D. et al. (2009) Identification of a dendritic cell receptor that couples sensing of necrosis to immunity. Nature 458 (7240): 899-903. | Joffre, O. P. et al. (2010) Efficient and versatile manipulation of the peripheral CD4+ T-cell compartment by antigen targeting to DNGR-1/CLEC9A. Eur. J. Immunol. 40 (5): 1255-1265. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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