IL-12 (p40/p70), Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityIL-12 (p40/p70), Mouse
CloneREA136
Host SpeciesRecombinant Human
Reactive Speciesmouse
IsotypeIgG1
Formatphycoerythrin (PE) conjugate
Size9 µg in 300 µL
Concentration1:10
ApplicationsIntracellular flow cytometry
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DescriptionIL-12 (p40/p70) Antibody, anti-mouse, PE, REAfinity™. Clone REA136 recognizes the 40 kDa p40 subunit of mouse IL-12, either in free form, as a homodimer or when it is expressed a part of heterodimeric IL-12 and IL-23 cytokines, where it associates with p35 and p19 subunit respectively. p40 shows homology to the extracellular domain of the members of haematopoietic cytokine-receptor family. Expression of p40 is restricted to cells producing IL-12. | Additional Information: Clone REA136 displays negligible binding to Fc receptors. |
Immunogenn/a
Other NamesIL12A, IL-12p35, IL-12A, Ll12a, P35, Il-12b, Il-12p40, Il12p40, P40
Gene, Accession #Gene ID: 16159, 16160
Catalog #130-102-955
Price$46
Order / More InfoIL-12 (p40/p70), Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesOppmann, B. et al. (2000) Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biological activities similar as well as distinct from IL-12. Immunity 13 (5): 715-725. | Trinchieri, G. et al. (2003) Interleukin-12 and the regulation of innate resistance and adaptive immunity. Nat. Rev. Immunol. 3 (2): 133-146.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

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