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Antigenic Specificity | TCRβ, Mouse |
Clone | REA318 |
Host Species | Recombinant Human |
Reactive Species | mouse |
Isotype | IgG1 |
Format | PE-Vio 615 conjugate |
Size | 30 µg in 200 µL |
Concentration | 1:50 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TCRβ Antibody, anti-mouse, PE-Vio® 615, REAfinity™. Clone REA318 recognizes the mouse T cell receptor beta chain (TCRβ). The T cell receptor (TCR) is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a disulfide-linked membrane-anchored heterodimeric glycoprotein normally consisting of the highly variable alpha and beta chains expressed as part of a complex with the invariant CD3 chain molecules. T cells expressing this receptor are referred to as TCRα/β T cells, though a minority of T cells express an alternate receptor, formed by variable gamma and delta chains, referred as TCRγ/δ T cells. TCRβ is expressed on TCRα/β T cells and thymocytes, NK1.1+ thymocytes and NK-T cells. | Additional information: Clone REA318 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | TCRB, TCRbeta, Tib |
Gene, Accession # | Gene ID: 21577 |
Catalog # | 130-130-039 |
Price | $141 |
Order / More Info | TCRβ, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Robins, H. S. et al. (2009) Comprehensive assessment of T-cell receptor β-chain diversity in αβ T cells. Blood 114 (19): 4099-4107. | Schumm, M. et al. (2013) Depletion of T-cell receptor alpha/beta and CD19 positive cells from apheresis products with the CliniMACS device. Cytotherapy 15 (10): 1253-1258. | Okuno, Y. et al. (2013) CD8+ CD122+ regulatory T cells contain clonally expanded cells with identical CDR3 sequences of the T-cell receptor β-chain. Immunology 139 (3): 309-317. |