Edit |   |
---|---|
Antigenic Specificity | SSRP1, Human/Mouse |
Clone | REA555 |
Host Species | Recombinant Human |
Reactive Species | human, mouse |
Isotype | IgG1 |
Format | phycoerythrin (PE) conjugate |
Size | 100 tests in 200 µL |
Concentration | 1:50 |
Applications | Intracellular flow cytometry, MICS (MACSima Imaging Cyclic Staining), Immunofluorescence, Immunohistochemistry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | SSRP1 Antibody, anti-human/mouse, PE, REAfinity™. Clone REA555 recognizes the human and mouse SSRP1 antigen, which is a protein including a component of the FACT (facilitates chromatin transcription) complex. FACT acts subsequent to transcription initiation to release RNA polymerase II from a nucleosome-induced block to productive transcription. It is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication, and DNA repair. | Additional information: Clone REA555 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | FACT, FACT80, T160, FACTp80, hSSRP1 |
Gene, Accession # | Gene ID: 6749, 20833 |
Catalog # | 130-132-369 |
Price | $362 |
Order / More Info | SSRP1, Human/Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Belotserkovskaya, R. et al. (2003) FACT facilitates transcription-dependent nucleosome alteration. Science 301: 1090-1093. | LeRoy, G. et al. (1998) Requirement of RSF and FACT for transcription of chromatin templates in vitro. Science 282: 1900-1900. | Orphanides, G. et al. (1998) FACT, a factor that facilitates transcript elongation through nucleosomes. Cell 92 (1): 105-116. |