Cadherin-16, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Edit | |
|---|---|
| Antigenic Specificity | Cadherin-16, Human |
| Clone | REAL807 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | n/a |
| Format | phycoerythrin (PE) conjugate |
| Size | 200 µL |
| Concentration | n/a |
| Applications | MICS (MACSima Imaging Cyclic Staining), Immunohistochemistry, Immunofluorescence |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Cadherin-16 Antibody, anti-human, PE, REAdye_lease™. Clone REAL807 is an antibody fragment derived from the full Cadherin-16 antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity. | Clone REAL807 recognizes the human Cadherin-16 glycoprotein, also known as Ksp-cadherin, encoded by the CDH16 gene. Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. Expression is exclusively in the kidney, where the protein functions as the principal mediator of homotypic cellular recognition, playing a role in the morphogenic direction of tissue development. | For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675). |
| Immunogen | n/a |
| Other Names | Ksp-cadherin, Kidney-specific cadherin, CDH16 |
| Gene, Accession # | n/a |
| Catalog # | 130-130-130 |
| Price | $470 |
| Order / More Info | Cadherin-16, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Wendeler, M. W. et al. (2004) Ksp-cadherin is a functional cell-cell adhesion molecule related to LI-cadherin. Exp. Cell Res. 294 (2): 345-355. | Thedieck, C. et al. (2005) Expression of Ksp-cadherin during kidney development and in renal cell carcinoma. Br. J. Cancer 92 (11): 2010-2017. | Cali, G. et al. (2012) CDH16/Ksp-cadherin is expressed in the developing thyroid gland and is strongly down-regulated in thyroid carcinomas. Endocrinology 153 (1): 522-534. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
Profile of MILTENYI BIOTEC B.V. & Co. KG