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Antigenic Specificity | TCR Vβ17a, Mouse |
Clone | REA647 |
Host Species | Recombinant Human |
Reactive Species | mouse |
Isotype | IgG1 |
Format | phycoerythrin (PE) conjugate |
Size | 9 µg in 300 µL |
Concentration | 1:10 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | TCR Vβ17a Antibody, anti-mouse, PE, REAfinity™. Clone REA647 recognizes the mouse V beta 17a T cell receptor (TCR Vβ17a). The T cell receptor is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a disulfide-linked membrane-anchored heterodimeric glycoprotein normally consisting of the highly variable alpha and beta chains expressed as part of a complex with the invariant CD3 chain molecules. The α and β TCR chains are composed of constant and variable regions, each encoded by distinct gene segments. TCR Vβ17a is a variant of the TCR β chain and is expressed on T cells having the a haplotype (eg. C57L, SJL, SWR) of the TCRβ gene complex. | Additional information: Clone REA647 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | TCR Vbeta17a, Gm16779, Tcrb-V9 |
Gene, Accession # | Gene ID: 100124681 |
Catalog # | 130-109-989 |
Price | $46 |
Order / More Info | TCR Vβ17a, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Kuchroo, V. K. et al. (1992) Experimental allergic encephalomyelitis mediated by cloned T cells specific for a synthetic peptide of myelin proteolipid protein. Fine specificity and T cell receptor V beta usage. J Immunol 148 (12): 3776-3782. | McDuffie, M. et al. (1992) I-E-independent deletion of V beta 17a+ T cells by Mtv-3 from the nonobese diabetic mouse. J Immunol 148 (7): 2097-9102. | Katz, J. et al. (1994) Expression of superantigen-like specificities on murine sjl/j-B lymphomas - antitumor v-Beta-17a+ T-lymphocytes use a diverse set of T-cell receptor v-alpha-chain gene-sequences. Int. J. Oncol. 4 (4): 839-847. |