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Antigenic Specificity | iNKT, Human |
Clone | REA1054 |
Host Species | Recombinant Human |
Reactive Species | human, nonhuman primate |
Isotype | IgG1 |
Format | biotin conjugate |
Size | 30 tests in 60 µL |
Concentration | 1:50 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | iNKT Antibody, anti-human, Biotin, REAfinity™. Clone REA1054 recognizes human iNKT cells. Natural killer T (NKT) cells represent a distinct lymphocyte population that co-expresses T cell and NK cell surface markers. A subset of human NKT cells, referred to as iNKT cells, expresses an invariant TCR α-chain with certain TCR β-chains (Vα24-Jα18 combined with Vβ11). The iNKT cells are implicated in immunoregulatory processes such as tolerance, host defense, and tumor surveillance. | Additional information: Clone REA1054 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | TCR Vα24-JαQ, TCR Va24-JαQ |
Gene, Accession # | Gene ID: 28659, 28747, 28582, 28581, 933 |
Catalog # | 130-118-031 |
Price | $93 |
Order / More Info | iNKT, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Montoya, J. C. et al. (2007) Characterization of human invariant natural killer T subsets in health and disease using a novel invariant natural killer T cell-clonotypic monoclonal antibody, 6B11. Immunology 122: 1-14. | Exley, M. et al. (2008) Selective activation, expansion, and monitoring of human iNKT cells with a monoclonal antibody specific for the TCR α-chain CDR3 loop. Eur. J. Immunol. 38: 1756-1766. |