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Antigenic Specificity | CD155, Mouse |
Clone | REA519 |
Host Species | Recombinant Human |
Reactive Species | mouse |
Isotype | IgG1 |
Format | phycoerythrin (PE) conjugate |
Size | 30 µg in 1 mL |
Concentration | 1:10 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD155 Antibody, anti-mouse, PE, REAfinity™. Clone REA519 recognizes the mouse CD155 antigen, which is a 70 kDa type I transmembrane glycoprotein in the immunoglobulin superfamily. CD155, also known as poliovirus receptor (PVR), belongs to a large family of Ig molecules called nectins and nectin-like proteins, which mediate cell-cell adhesion, cell migration, and serve as entry receptors for viruses. CD155 and its family member CD112 (nectin-2) are the ligands for the activating cell-surface receptor DNAM-1 on CD8+ T cells and natural killer (NK) cells. Mouse CD155 is found on a wide variety of cells of hematopoietic origin, on CD4+ CD8+ thymocytes, regulatory T cells, other activated T cells, NKT cells, and at cell junctions on the primary vascular endothelial cells. | Additional information: Clone REA519 displays negligible binding to Fc receptors. |
Immunogen | n/a |
Other Names | PVR, HVED, PVS, Taa1, TAGE4, mE4, NECL-5 |
Gene, Accession # | Gene ID: 52118 |
Catalog # | 130-107-807 |
Price | $66 |
Order / More Info | CD155, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Fuchs, A. et al. (2004) Cutting Edge: CD96 (Tactile) promotes NK cell-target cell adhesion by interacting with the poliovirus receptor (CD155). J Immunol 172: 3994-3998. | Tahara-Hanaoka, S. et al. (2006) Tumor rejection by the poliovirus receptor family ligands of the DNAM-1 (CD226) receptor. Blood 107: 1491-1496. | Seth, S. et al. (2007) The murine pan T cell marker CD96 is an adhesion receptor for CD155 and nectin-1. Biochem. Biophys. Res. Commun. 364 (4): 959-965. |