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Antigenic Specificity | CD218 (IL-18Rα), Human |
Clone | H44 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1κ |
Format | phycoerythrin (PE) conjugate |
Size | 100 tests in 1 mL |
Concentration | 1:11 |
Applications | Flow cytometry |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD218 (IL-18Rα) Antibody, anti-human, PE. Clone H44 recognizes the CD218 antigen, which is also known as interleukin-18 receptor α chain (IL-18Rα) receptor, is an heterodimeric receptor complex and composed of the IL-18Rα chain and the IL-1 receptor accessory protein-like (IL-1RacPL) or IL-18Rβ chain. CD218 represents the ligand-binding chain, whereas IL-18Rβ is suggested to assist in the formation of a high affinity complex and mediates intracellular signals. IL-18R is expressed on a variety of cells including macrophages, neutrophils, natural killer (NK) cells, endothelial, and smooth muscle cells and an upregulated expression is observed on naive T cells, T helper cell type 1 (T?1) cells, and B cells, in the presence of IL-12. |
Immunogen | n/a |
Other Names | IL18R1, CD218a, CDw218a, IL-1Rrp, IL18RA, IL1RRP |
Gene, Accession # | n/a |
Catalog # | 130-101-726 |
Price | $264 |
Order / More Info | CD218 (IL-18Rα), Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
Product Specific References | Kim, S. H. et al. (2001) Functional reconstitution and regulation of IL-18 activity by the IL-18Rβ chain. J Immunol 166: 148-154. | Nakamura, S. et al. (2000) Expression and responsiveness of human interleukin-18 receptor (IL-18R) on hematopoietic cell lines. Leukemia 14 (6): 1052-1059. |