IFNAR2, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | IFNAR2, Human |
| Clone | REA124 |
| Host Species | Recombinant Human |
| Reactive Species | human |
| Isotype | IgG1 |
| Format | APC-Vio 770 conjugate |
| Size | 30 tests in 300 µL |
| Concentration | 1:11 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | IFNAR2 Antibody, anti-human, APC-Vio® 770, REAfinity™. Clone REA124 recognizes the human interferon α/β receptor 2 (IFNAR2) antigen, a 100 kDa single-pass type I membrane protein that forms one of the two chains of a receptor for the type I interferons IFN-α, IFN-β, and IFN-ω. These interferons are a group of structurally and functionally related proteins, induced by viruses or double-stranded RNA and defined by their ability to establish an antiviral state in cells. IFNAR2 is expressed on most lymphocytes, monocytes, and granulocytes, although IFNAR2 expression is higher on monocytes and granulocytes than on lymphocytes. It is involved in IFN-mediated STAT1, STAT2, and STAT3 activation. The alternatively spliced isoform of IFNAR2 is a potent inhibitor of type I IFN receptor activity. | Additional information: Clone REA124 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | Interferon α/β receptor 2 (IFN-R-2, IFN-α binding protein, IFN-α/β receptor 2), IFN-R, IFN-alpha-REC, IFNABR, IFNARB |
| Gene, Accession # | Gene ID: 3455 |
| Catalog # | 130-099-554 |
| Price | $158 |
| Order / More Info | IFNAR2, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Constantinescu, S. N. et al. (1995) Expression and signaling specificity of the IFNAR chain of the type I interferon receptor complex. Proc. Natl. Acad. Sci. U.S.A. 92 (23): 10487-10491. | Novick, D. et al. (1995) Soluble and membrane-anchored forms of the human IFN-alpha/beta receptor. J. Leukoc. Biol. 57 (5): 712-718. | Novick, D. et al. (1994) The human interferon alpha/beta receptor: characterization and molecular cloning. Cell 77 (3): 391-400. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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