TCR Vβ7.2, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG

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Antigenic SpecificityTCR Vβ7.2, Human
CloneREA677
Host SpeciesRecombinant Human
Reactive Specieshuman
IsotypeIgG1
FormatVio Bright V423 conjugate
Size100 tests in 200 µL
Concentration1:50
ApplicationsFlow cytometry
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DescriptionTCR Vβ7.2 Antibody, anti-human, Vio® Bright V423, REAfinity™. Clone REA677 recognizes the human Vβ7.2 T cell receptor (TCR Vβ7.2). The TCR is responsible for recognizing antigens bound to major histocompatibility complex (MHC) molecules. It is a disulfide-linked membrane-anchored heterodimeric glycoprotein normally consisting of the highly variable α and β chains expressed as part of a complex with the invariant CD3 chain molecules. It is suggested that T cells expressing TCRs with Vβ7.2 are protective against a pathogenic immune response in Sjoegren's syndrome. TCR Vβ7.2 is expressed on a subset of α/β T cells. | Additional information: Clone REA677 displays negligible binding to Fc receptors. |
Immunogenn/a
Other NamesTCR Vb7.2, TCR Vbeta7.2
Gene, Accession #Gene ID: 28596, 6957
Catalog #130-131-324
Price$500
Order / More InfoTCR Vβ7.2, Human Antibody from MILTENYI BIOTEC B.V. & Co. KG
Product Specific ReferencesZhao, T. M. et al. (1994) A genetically determined insertion/deletion related polymorphism in human T cell receptor beta chain (TCRB) includes functional variable gene segments. J. Exp. Med. 180 (4): 1405-1414. | Manavalan, S. J. et al. (2004) Genomic absence of the gene encoding T cell receptor Vbeta7.2 is linked to the presence of autoantibodies in Sjogren's syndrome. Arthritis Rheum 50 (1): 187-198. | Wei, S. et al. (1994) The extent of the human germline T-cell receptor V beta gene segment repertoire. Immunogenetics 40 (1): 27-36.
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-Straße 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197

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