Ly-49F, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG
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| Antigenic Specificity | Ly-49F, Mouse |
| Clone | REA1021 |
| Host Species | Recombinant Human |
| Reactive Species | mouse |
| Isotype | IgG1 |
| Format | biotin conjugate |
| Size | 30 µg in 200 µL |
| Concentration | 1:50 |
| Applications | Flow cytometry |
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
| Description | Ly-49F Antibody, anti-mouse, Biotin, REAfinity™. Clone REA1021 recognizes the mouse Ly-49F antigen (killer cell lectin-like receptor 6), a type II transmembrane natural killer (NK) cell receptor belonging to the Ly-49 family. Members of the Ly-49 family are homodimeric C-type lectin receptors, recognizing MHC class I molecules as ligands and include activating and inhibitory receptor molecules. The inhibitory receptor Ly-49F is expressed on subsets of NK cells, NK-T cells, and on a subpopulation of memory T cells in C57BL/6 mice, but not AKR/J, BALB/c, C3H/HeN, DBA/1, or SJL mice. IL-21 selectively down-regulates Ly-49F on mature NK cells. | Additional information: Clone REA1021 displays negligible binding to Fc receptors. |
| Immunogen | n/a |
| Other Names | Klra6, Lymphocyte antigen 49f, T-cell surface glycoprotein Ly-49F |
| Gene, Accession # | Gene ID: 16637 |
| Catalog # | 130-117-273 |
| Price | $64 |
| Order / More Info | Ly-49F, Mouse Antibody from MILTENYI BIOTEC B.V. & Co. KG |
| Product Specific References | Smith, H. R. et al. (1994) Ly-49 multigene family expressed by IL-2-activated NK cells. J Immunol 153 (3): 1068-1079. | Hanke, T. et al. (1999) Direct assessment of MHC class I binding by seven Ly49 inhibitory NK cell receptors. Immunity 11 (1): 67-77. | Gays, F. et al. (2005) Multiple cytokines regulate the NK gene complex-encoded receptor repertoire of mature NK cells and T cells. J Immunol 175 (5): 2938-2947. |
MILTENYI BIOTEC B.V. & Co. KG
MILTENYI BIOTEC B.V. & Co. KG
Friedrich-Ebert-StraÃe 68
51429 Bergisch Gladbach GERMANY
P: +49 2204 8306-0
F: +49 2204 85197
macs@miltenyibiotec.de
https://www.miltenyibiotec.com
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